In the context of LAAO, what does CHA2DS2-VASc >/= 3 indicate?

The CHA2DS2-VASc score is a clinical tool used to assess the risk of stroke in patients with atrial fibrillation. A score of 3 or greater indicates a high risk for stroke, prompting consideration for anticoagulation therapy or interventions such as Left Atrial Appendage Occlusion (LAAO). The score incorporates several factors, including congestive heart failure, hypertension, age, diabetes, stroke history, vascular disease, and sex. Each component contributes to the overall stroke risk assessment, with higher scores reflecting an increased likelihood of thromboembolic events. Thus, a CHA2DS2-VASc score of 3 or more signifies that a patient is at significant risk for stroke, highlighting the need for effective management strategies like LAAO to mitigate this risk.