What hemodynamic changes may occur during LAAO?

Shifts in left atrial pressure and changes in pulmonary venous flow are significant hemodynamic changes that can occur during Left Atrial Appendage Occlusion (LAAO). During the procedure, as the left atrial appendage is occluded, there are immediate effects on the hemodynamics of the left atrium and the surrounding structures. The closure of the appendage can lead to a decrease in the volume of blood entering the left atrium, consequently affecting the left atrial pressure.

As blood flow dynamics change, the alteration in the pressure can affect the flow of blood entering the pulmonary veins, since the left atrium is directly impacted by the venous return from the pulmonary circulation. If left atrial pressure reduces, it might enhance the efficiency of pulmonary venous drainage. This can also influence systemic circulation dynamics since effective left atrial function is crucial for optimal left ventricular filling and maintaining normal heart function.

This understanding of hemodynamic changes is essential for clinicians performing or assessing the outcomes of LAAO, as it allows for better monitoring and management of patients post-procedure.