What is a significant risk factor that may lead to the consideration of LAAO?

The presence of non-valvular atrial fibrillation with a high CHA2DS2-VASc score is a significant risk factor leading to the consideration of Left Atrial Appendage Occlusion (LAAO). This scoring system helps to assess the risk of stroke in patients with atrial fibrillation by considering various factors such as heart failure, hypertension, age, diabetes, previous strokes, and vascular disease. A higher score indicates a greater risk for stroke, thus supporting the decision to implement LAAO as a preventative measure.

In patients with atrial fibrillation, the left atrial appendage is a common site for thrombus formation. By occluding this appendage, LAAO reduces the risk of thromboembolic events, particularly strokes. Therefore, those with a non-valvular type of atrial fibrillation and elevated stroke risk are prime candidates for this intervention, highlighting why this factor is critical in determining the need for LAAO.