What is the role of anticoagulation therapy in patients undergoing LAAO?

The role of anticoagulation therapy in patients undergoing Left Atrial Appendage Occlusion (LAAO) is critical in minimizing the risk of thromboembolism, particularly stroke, associated with atrial fibrillation. Before the procedure, patients are typically placed on anticoagulants to prevent the formation of blood clots in the left atrial appendage, which is a common source of emboli in patients with atrial fibrillation.

After the LAAO procedure, anticoagulation continues for a specified duration to allow for proper healing of the occlusion site and to further mitigate the risk of any potential thrombus formation that may occur during the immediate post-operative period. This dual-phase approach - administering anticoagulants both before and after the LAAO - is vital for maximizing patient safety and outcomes.

Thus, the comprehensive management strategy incorporating anticoagulation before and after the procedure is fundamental to the overall effectiveness of LAAO as a means of stroke prevention in these patients.