Where do clinicians aim for transseptal access during LAAO placement?

During LAAO procedures, clinicians aim for inferior posterior transseptal access primarily to facilitate optimal positioning and delivery of the occlusion device to the left atrial appendage. This location, typically at the fossa ovalis, allows for the most straightforward pathway to reach the left atrium and subsequently the appendage, which is key in reducing the risk of procedural complications and ensuring successful closure of the appendage to mitigate stroke risk.

Achieving access in this region promotes safety by minimizing the potential for encountering critical structures and allows for effective visualization and manipulation of the occlusion device. The inferior posterior region is typically less affected by anatomical variability and enhances the physician's ability to orient and deploy the device accurately. This positioning is advantageous for both the immediate procedural setup and the long-term effectiveness of the occlusion strategy.