Why are definitions of non-valvular atrial fibrillation important for LAAO eligibility?

Understanding the importance of defining non-valvular atrial fibrillation (AF) is crucial for assessing LAAO eligibility because this definition helps identify patients who would benefit from the procedure. Non-valvular atrial fibrillation refers specifically to AF that is not caused by issues with the heart's valves.

In the context of LAAO, patients with significant valvular heart disease may not be appropriate candidates for the procedure, as their risk factors and treatment requirements differ from those of patients with non-valvular AF. By confirming that candidates are without significant valve disease, the process ensures that the focus remains on individuals whose AF is isolated from valvular complications, making them suitable for the LAAO intervention aimed at reducing the risk of stroke through the occlusion of the left atrial appendage.

Thus, the distinction between non-valvular and valvular AF is essential to appropriately select patients who will derive the most benefit from the LAAO procedure without the complicating factors associated with significant valve disease, ensuring better outcomes and safety during and after the intervention.